Methylaminoformyl chloride
- CAS NO.：6452-47-7
- Empirical Formula: C2H4ClNO
- Molecular Weight: 93.51
- MDL number: MFCD08703300
- EINECS: 229-253-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:24:57
What is Methylaminoformyl chloride?
The Uses of Methylaminoformyl chloride
Methylcarbamoyl Chloride is used as a reagent in the synthesis of acylprolinamides as a new class of peptide deformylase inhibitors with in vivo antibacterial activity. Methylcarbamoyl Chloride is also used as a reagent in the synthesis of carbamate derivatives as potential dual-binding site acetylcholinesterase inhibitors.
Synthesis Reference(s)
Journal of the American Chemical Society, 72, p. 1888, 1950 DOI: 10.1021/ja01161a009
Properties of Methylaminoformyl chloride
| Melting point: | 45°C |
| Boiling point: | 93°C (dec.) |
| Density | 1.185±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | Acetonitrile, Chloroform (Slightly), DMSO |
| form | Solid |
| pka | 10.67±0.46(Predicted) |
| color | White to Off-White |
| Stability: | Air Sensitive, Hygroscopic, Moisture Sensitive, Volatile |
| CAS DataBase Reference | 6452-47-7(CAS DataBase Reference) |
Safety information for Methylaminoformyl chloride
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P501:Dispose of contents/container to..… |
Computed Descriptors for Methylaminoformyl chloride
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