Methyl dimethoxyacetate
Synonym(s):Glyoxylic acid methyl ester dimethyl acetal
- CAS NO.:89-91-8
- Empirical Formula: C5H10O4
- Molecular Weight: 134.13
- MDL number: MFCD00008484
- EINECS: 201-950-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:24:13
What is Methyl dimethoxyacetate?
Chemical properties
CLEAR COLOURLESS TO VERY SLIGHTLY YELLOW LIQUID
The Uses of Methyl dimethoxyacetate
Methyl dimethoxyacetate has been used:
- in Claisen acylation of active hydrogen compounds
- in preparation of 3, 9-disubstituted 2,4,8,10-tetroxaspiro [5.5] undecane
- as Lithium enolate precursor
- as acylating reagent for cycloalkanone enolates and amino alcohols
What are the applications of Application
Methyl dimethoxyacetate is an acylating reagent for amino alcohols
Properties of Methyl dimethoxyacetate
| Boiling point: | 67 °C/18 mmHg (lit.) |
| Density | 1.096 g/mL at 25 °C (lit.) |
| refractive index | n |
| Flash point: | 146 °F |
| storage temp. | 2-8°C |
| solubility | Chloroform (Sparingly), Methanol (Slightly) |
| form | Liquid |
| color | Clear colorless to very slightly yellow |
| Sensitive | Moisture Sensitive |
| BRN | 1757582 |
| InChI | InChI=1S/C5H10O4/c1-7-4(6)5(8-2)9-3/h5H,1-3H3 |
| CAS DataBase Reference | 89-91-8(CAS DataBase Reference) |
| NIST Chemistry Reference | Acetic acid, dimethoxy-, methyl ester(89-91-8) |
| EPA Substance Registry System | Acetic acid, dimethoxy-, methyl ester (89-91-8) |
Safety information for Methyl dimethoxyacetate
| Signal word | Warning |
| Pictogram(s) |
![]() Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H227:Flammable liquids |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P280:Wear protective gloves/protective clothing/eye protection/face protection. P403+P235:Store in a well-ventilated place. Keep cool. P501:Dispose of contents/container to..… |
Computed Descriptors for Methyl dimethoxyacetate
| InChIKey | NZTCVGHPDWAALP-UHFFFAOYSA-N |
| SMILES | C(OC)(=O)C(OC)OC |
Methyl dimethoxyacetate manufacturer
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