METHYL 7-METHOXY-1H-INDAZOLE-3-CARBOXYLATE
- CAS NO.：885278-95-5
- Empirical Formula: C10H10N2O3
- Molecular Weight: 206.2
- MDL number: MFCD07371596
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-07-23 08:30:07
What is METHYL 7-METHOXY-1H-INDAZOLE-3-CARBOXYLATE?
The Uses of METHYL 7-METHOXY-1H-INDAZOLE-3-CARBOXYLATE
Methyl 7-Methoxy-2H-indazole-3-carboxylate is an intermediate in the synthesis of 7-Hydroxy Granisetron (H942675), a metabolite of Granisetron (G780000), a specific serotonin (5HT3) receptor antagonist. Used as an antiemetic. Granisetron HCl is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy. Its main effect is to reduce the activity of the vagus nerve. It does not have much effect on vomiting due to motion sickness. This drug does not have any effect on dopamine receptors or muscarinic receptor.
Properties of METHYL 7-METHOXY-1H-INDAZOLE-3-CARBOXYLATE
| Melting point: | 141-142 °C |
| Boiling point: | 382.2±22.0 °C(Predicted) |
| Density | 1.313±0.06 g/cm3(Predicted) |
| pka | 11.26±0.40(Predicted) |
Safety information for METHYL 7-METHOXY-1H-INDAZOLE-3-CARBOXYLATE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for METHYL 7-METHOXY-1H-INDAZOLE-3-CARBOXYLATE
New Products
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