Methyl 4-aminopyridine-2-carboxylate

CAS NO.：71469-93-7
Empirical Formula: C7H8N2O2
Molecular Weight: 152.15
MDL number: MFCD00956000
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-12 09:12:00

What is Methyl 4-aminopyridine-2-carboxylate?

Chemical properties

Off-white solid

The Uses of Methyl 4-aminopyridine-2-carboxylate

Methyl 4-aminopyridine-2-carboxylate

Synthesis

Methyl 4-aminopyridine-2-carboxylate is synthesised using Methyl 4-azidopyridine-2-carboxylate as a raw material by chemical reaction. The specific synthesis steps are as follows:
4-Azido-pyridine-2-carboxylic acid methyl ester (3.9 g, 22 mmol, 1 eq) was solubilized in methanol (50 mL) and palladium 10 percent w on carbon (400 mg) was added. The mixture was stirred at room temperature over 4 bars pressure of hydrogen until completion of the reaction. The mixture was then filtered over a short pad of celite, and rinsed with methanol to afford the expected compound as a yellow powder (3.0 g, 90percent yield).
Methyl 4-aminopyridine-2-carboxylate synthesis

Properties of Methyl 4-aminopyridine-2-carboxylate

Melting point:	129-130°
Boiling point:	333.7±22.0 °C(Predicted)
Density	1.238±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
form	powder to crystal
pka	4.35±0.10(Predicted)
color	White to Light yellow

Safety information for Methyl 4-aminopyridine-2-carboxylate

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.