Methyl 1-acetyl-2-oxoindoline-6-carboxylate
- CAS NO.：676326-36-6
- Empirical Formula: C12H11NO4
- Molecular Weight: 233.22
- MDL number: MFCD18251630
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-08-08 17:45:00
What is Methyl 1-acetyl-2-oxoindoline-6-carboxylate?
The Uses of Methyl 1-acetyl-2-oxoindoline-6-carboxylate
Methyl 1-Acetyl-2-oxoindoline-6-carboxylate is a reagent used in the preparation of Nintedanib (N478290), an angiokinase inhibitor and is used in the treatment of idiopathic pulmonary fibrosis. Also inhibits the process blood vessel formation which may be used to assist in cancer therapy.
Properties of Methyl 1-acetyl-2-oxoindoline-6-carboxylate
| Boiling point: | 489.5±45.0 °C(Predicted) |
| Density | 1.330 |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | -1.94±0.20(Predicted) |
| form | Solid |
| color | Off-White to Pale Red |
Safety information for Methyl 1-acetyl-2-oxoindoline-6-carboxylate
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Methyl 1-acetyl-2-oxoindoline-6-carboxylate
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