BIBF 1202
- CAS NO.：894783-71-2
- Empirical Formula: C30H31N5O4
- Molecular Weight: 525.6
- MDL number: MFCD28167767
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-11 19:39:08
What is BIBF 1202?
Description
BIBF 1202 is an active metabolite of the VEGFR, FGFR, and PDGFR inhibitor BIBF 1120 (nintedanib; ). It is formed from BIBF 1120 by intracellular esterases. BIBF 1202 inhibits VEGFR2 with an IC50 value of 62 nM.
The Uses of BIBF 1202
Nintedanib Carboxylic Acid is a related compound of Intedanib (I666650), an indolinone derivative that inhibits angiokinase and an antitumor agent.
Properties of BIBF 1202
| Melting point: | >216°C (dec.) |
| Boiling point: | 759.5±60.0 °C(Predicted) |
| Density | 1.331±0.06 g/cm3(Predicted) |
| storage temp. | Refrigerator |
| solubility | Aqueous Base (Slightly, Heated) |
| form | Solid |
| pka | 3.94±0.20(Predicted) |
| color | Light Yellow to Yellow |
Safety information for BIBF 1202
Computed Descriptors for BIBF 1202
New Products
3-AMINO-3-(2-FLUORO-PHENYL)-PROPIONIC ACID Pentadecanoic acid Hendecanoic acid 2-AMINO-3-METHYLQUINOLINE HYDROCHLORIDE 3-Hydroxypropionitrile DL-3-Amino-3-(2-methoxyphenyl)propionic acid 5-Bromo-2-Fluoropyridine 2,3-Diamino-5-Chloropyridine 2-Amino-3-Hydroxypyridine 2,6-Diamino Pyridine 4-Amino-2-Chloropyridine 2-Hydroxy-4-Picoline 4-(4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 4-Bromo-3-(ethoxymethyl)benzoic acid 2,4-Dichloro-5-methoxyaniline 4,6-Dichloro-2-(propylthio)pyrimidin-5-amine N2-Isobutyryl-2'-O-methylguanosine 2-chloro-5-methylpyridin-4-amine 4-Bromobenzaldehyde 2-Chloro-6-nitro benzothiazole 2-Amino-4-phenyl-thiazole 4-Chloro-2-methyl quinoline 2-(Chloromethyl) quinazolin-4(3H)-one 5-Phenyl-[1,3,4]-thiadiazol-2-amineRelated products of tetrahydrofuran
![1,3-DiMethyl 2-[4-(Methoxycarbonyl)-2-nitrophenyl]propanedioate](https://img.chemicalbook.in/CAS/GIF/1160293-27-5.gif)
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