BIBF 1202
- CAS NO.：894783-71-2
- Empirical Formula: C30H31N5O4
- Molecular Weight: 525.6
- MDL number: MFCD28167767
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-27 17:00:41
What is BIBF 1202?
Description
BIBF 1202 is an active metabolite of the VEGFR, FGFR, and PDGFR inhibitor BIBF 1120 (nintedanib; ). It is formed from BIBF 1120 by intracellular esterases. BIBF 1202 inhibits VEGFR2 with an IC50 value of 62 nM.
The Uses of BIBF 1202
Nintedanib Carboxylic Acid is a related compound of Intedanib (I666650), an indolinone derivative that inhibits angiokinase and an antitumor agent.
Properties of BIBF 1202
| Melting point: | >216°C (dec.) |
| Boiling point: | 759.5±60.0 °C(Predicted) |
| Density | 1.331±0.06 g/cm3(Predicted) |
| storage temp. | Refrigerator |
| solubility | Aqueous Base (Slightly, Heated) |
| form | Solid |
| pka | 3.94±0.20(Predicted) |
| color | Light Yellow to Yellow |
Safety information for BIBF 1202
Computed Descriptors for BIBF 1202
New Products
2-(2-Chlorophenyl)glycine Propiolic Acid 1-(3-Hydroxy-4-methoxyphenyl)-2-nitroethene (±)-amino(2-fluorophenyl)acetic acid trans-3-Benzyloxy-4-methoxy-beta-nitrostyrene 1-Pentadecanol 4-(4-Αminophenyl)-3-Morpholinone 3-Morpholino-1-(4-(2-oxopiperidin-1-yl) phenyl)-5,6-dihyropyridin-2-(1H)-one 1-(4-Aminophenyl)-3-morpholino-5,6-dihydropyridin-2(1H)-one N-cyanoacetylurethane 1H-IndazoleRelated products of tetrahydrofuran
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