MeOSuc-Ala-Ala-Pro-Val-chloromethylketone
Synonym(s):N-(Methoxysuccinyl)-L -alanyl-L -alanyl-L -prolyl-L -valine chloromethylketone
- CAS NO.：65144-34-5
- Empirical Formula: C22H35ClN4O7
- Molecular Weight: 502.99
- MDL number: MFCD00077136
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:52:16
What is MeOSuc-Ala-Ala-Pro-Val-chloromethylketone?
The Uses of MeOSuc-Ala-Ala-Pro-Val-chloromethylketone
A potent irreversible inhibitor of human leukocyte elastase
What are the applications of Application
N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone is an inhibitor of neutrophil elastase
Definition
ChEBI: A tripeptide derived from methoxysuccinyl-Ala-Ala-Pro-Val by conversion of the terminal carboxy group to the corresponding chloromethyl ketone.
General Description
N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone is a tetrapeptide, cell-permeable and non-cytotoxic inhibitor.
Biochem/physiol Actions
N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone acts as a competitive inhibitor of human leukocyte elastase (HLE).
Properties of MeOSuc-Ala-Ala-Pro-Val-chloromethylketone
| Melting point: | 159-161 °C |
| Boiling point: | 809.4±65.0 °C(Predicted) |
| Density | 1.234±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | ethanol: 50 mg/mL, clear, colorless |
| pka | 13.05±0.20(Predicted) |
| form | Solid |
| Sensitive | Moisture Sensitive |
| BRN | 6167019 |
Safety information for MeOSuc-Ala-Ala-Pro-Val-chloromethylketone
Computed Descriptors for MeOSuc-Ala-Ala-Pro-Val-chloromethylketone
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