LL-37
- CAS NO.：154947-66-7
- Empirical Formula: C205H340N60O53
- Molecular Weight: 0
- MDL number: MFCD09264694
- EINECS: 211-519-9
- Update Date: 2026-07-23 14:48:42
What is LL-37?
Origin
Mammalian AMPs belong to the defensin and cathelicidin families. So far, there is a unique cathelicidin peptide found in 1995 and called human cationic antimicrobial peptide (hCAP18). Its active part starts with double leucine and consists of 37-amino acids at the C-terminus, so which is called LL-37.
Benefits
LL-37 is an important part of the human immune system, which can resist various pathogens. A plethora of experiments have demonstrated that it has the multifunctional effects of immune regulation, in addition to antimicrobial activity.
Significantly boosts immune function;
Fights inflammation; Prevents cancer progression;
Accelerates wound healing;
Lowers the risk of heart disease; Prevents lung injury;
Promotes bone repair.
Side Effects
LL-37 side effects are very uncommon. LL-37 induced apparent rosacea symptoms, erythema, and telangiectasia on the skin. Side effects associated with LL-37 may include the following:
Increased inflammation
Induction of autoimmune disease
Depression
Damage to sperm surface membranes
Storage
Store at -20°C
Properties of LL-37
| solubility | Water: 1 mg/ml |
| form | A lyophilized powder |
| color | White to off-white |
| Water Solubility | Soluble to 1 mg/ml in water |
Safety information for LL-37
Computed Descriptors for LL-37
| InChIKey | POIUWJQBRNEFGX-XAMSXPGMSA-N |
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