ADRENOMEDULLIN (HUMAN)
- CAS NO.：148498-78-6
- Empirical Formula: C264H406N80O77S3
- Molecular Weight: 6028.73324
- MDL number: MFCD00211549
- Update Date: 2026-05-28 01:28:33
What is ADRENOMEDULLIN (HUMAN)?
The Uses of ADRENOMEDULLIN (HUMAN)
Peptide elicits potent hypotensive effect, comparable to calcitonin gene-related peptide. Plays a key role in regulating endometrial angiogenesis.
General Description
Adrenomedullin (ADM) human comprises of 52 amino acids and has amine group in the C-terminal tyrosine residue. It also has a N-terminal ring structure and belongs to calcitonin peptide family. ADM has vasodilatory function and is mapped to human chromosome 11p15.4. Adrenomedullin is highly expressed in endothelial cells. Adrenomedullin controls a majority of cellular processes using cyclic adenosine monophosphate (cAMP) as a messenger. It interacts with calcitonin receptor-like receptor (CRLR) and receptor activity modifying protein 2 (RAMP2). ADM contributes to invasion activity in brain tumor cell lines. ADM signalling plays a key role in tumor progression, especially in acute myeloid leukemia.
Biochem/physiol Actions
Peptide elicits potent hypotensive effect, comparable to calcitonin gene-related peptide. Plays a key role in regulating endometrial angiogenesis.
Properties of ADRENOMEDULLIN (HUMAN)
| storage temp. | -20°C |
| solubility | Soluble at 1mg/ml in 1% acetic acid |
| form | powder |
Safety information for ADRENOMEDULLIN (HUMAN)
Computed Descriptors for ADRENOMEDULLIN (HUMAN)
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