LIPOXIN B4
- CAS NO.：98049-69-5
- Empirical Formula: C20H32O5
- Molecular Weight: 352.47
- MDL number: MFCD00870250
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-17 09:03:53
What is LIPOXIN B4?
The Uses of LIPOXIN B4
5(S),14(R)-Lipoxin B4 is a positional isomer of LXA4.
The Uses of LIPOXIN B4
Lipoxins are a series of anti-inflammatory lipid mediators whose brief appearance generally signals the resolution of inflammation. Lipoxin A4 (LXA4) is a potent inhibitor of leukotriene (LT)-triggered polymorphonuclear neutrophil (PMN)-endothelial cell interaction and also blocks PMN migration stimulated by LTB4. LXB4 is a positional isomer of LXA4 produced by the metabolism of 15-HETE or 15-HpETE by human leukocytes. At a concentration of 10-7 M, LXB4 inhibits PMN migration stimulated by LTB4 and inhibits LTB4-induced adhesion of PMNs with an IC50 value of ~3 X 10-10 M.
What are the applications of Application
5(S),14(R)-Lipoxin B4 is a positional isomer of LXA4
Definition
ChEBI: Lipoxin B4 is a C20 hydroxy fatty acid having (5S)-, (14R)- and (15S)-hydroxy groups as well as (6E)- (8Z)-, (10E)- and (12E)-double bonds. It has a role as a human metabolite. It is a lipoxin, a long-chain fatty acid and a hydroxy polyunsaturated fatty acid. It is a conjugate acid of a lipoxin B4(1-).
Properties of LIPOXIN B4
| storage temp. | -20°C |
| solubility | DMF: >50 mg/ml; Ethanol: >50 mg/ml; PBS pH 7.2: >1 mg/ml (from 13(S)-HODE) |
Safety information for LIPOXIN B4
Computed Descriptors for LIPOXIN B4
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