Lg 6-102
- CAS NO.：132798-30-2
- Empirical Formula: C22H29NO3.ClH
- Molecular Weight: 391.936
- MDL number: MFCD00892975
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:51:37
What is Lg 6-102?
Description
LG 6-102 is a new propafenone-related antiarrhythmic agent with good oral activity in rats.
in vivo
Rats were treated with LG 6-101 (16, 32, 64, 128, 256 mg kg-1 bodyweight), LG 6-102 (4, 8, 16, 32, 64 mg kg-1 bodyweight) and propafenone (32, 64, 128, 256 mg kg-1 bodyweight) by gavage twice daily during 4 days. Both, LG 6-101 and LG 6-102 showed strong antiarrhythmic effects against arrhythmias induced on the fifth day by infusion of aconitine (10 micrograms kg-1 min-1). LG 6-102 was significantly more effective against cardiac arrest caused by infusion of aconitine (P less than or equal to 0.05) than LG 6-101._x000D_ _x000D_ Reference: Naunyn Schmiedebergs Arch Pharmacol. 1992 Apr;345(4):473-7. https://pubmed.ncbi.nlm.nih.gov/1620247/
Safety information for Lg 6-102
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