LATHOSTEROL

Synonym(s):3β-Hydroxy-5α,7-cholestene;5α-cholest-7-en-3β-ol;Lathosterol

CAS NO.：80-99-9
Empirical Formula: C27H46O
Molecular Weight: 386.65
MDL number: MFCD00056176
SAFETY DATA SHEET (SDS)
Update Date: 2026-04-22 18:57:36

What is LATHOSTEROL?

The Uses of LATHOSTEROL

A Cholesterol (C432501) metabolite. Lathosterol (indicating cholesterol synthesis) and Sitosterol (indicating cholesterol absorption) also decreased with deteriorating health. Low Lathosterol, Sitosterol (S497050), and Cholesterol (C432501) predicted mortality additively and independently of each other.

The Uses of LATHOSTEROL

Lathosterol has been used as a standard for the estimation of the concentrations of cholesterol and plant sterols.

The Uses of LATHOSTEROL

5α-Cholest-7-en-3β-ol was used as a substrate in enzymatic assay for plasma cholesterol. It was used to supplement diet of Daphnia galeata to study the effect on life-history traits.

What are the applications of Application

5α-Cholest-7-en-3β-ol is used as a substrate in enzymatic assay for plasma cholesterol

Definition

ChEBI: A cholestanoid that is (5alpha)-cholest-7-ene substituted by a beta-hydroxy group at position 3.

General Description

Lathosterol is a cholesterol synthesis precursor.

Biochem/physiol Actions

5α-Cholest-7-en-3β-ol (Lathosterol) is an intermediate in cholesterol biosynthesis pathway. Lathosterol in serum is carried on lipoproteins and is indicative of the rate of cholesterol synthesis. It acts as a marker of synthesis of cholesterol and is not affected by dietary consumption of cholesterol.

Properties of LATHOSTEROL

Melting point:	126°C
Boiling point:	452.8°C (rough estimate)
Density	0.9610 (rough estimate)
refractive index	1.5250 (estimate)
storage temp.	-20°C
solubility	Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly, Sonicated)
form	Solid
pka	15.10±0.70(Predicted)
color	White to Off-White