L-Arginine, N2-[[3-[(2,1,3-benzothiadiazol-4-ylsulfonyl)aMino]-2-thienyl]carbonyl]-

The Uses of L-Arginine, N2-[[3-[(2,1,3-benzothiadiazol-4-ylsulfonyl)aMino]-2-thienyl]carbonyl]-

EG 00229 is a useful intermediate.

Definition

ChEBI: EG00229 is a member of the class of thiophenes that is thiophene substituted by a carbonyl-L-arginine and (2,1,3-benzothiadiazole-4-sulfonyl)amino groups at positions 2 and 3. It is an inhibitor of the neuropilin-1 and VEGF-A interaction and a potential anti-cancer agent. It has a role as an antineoplastic agent, a neuropilin receptor antagonist and an angiogenesis inhibitor. It is a benzothiadiazole, a sulfonamide, a member of thiophenes, a secondary carboxamide, a L-arginine derivative and a dicarboxylic acid monoamide.