1018927-63-3
Product Name:
L-Arginine, N2-[[3-[(2,1,3-benzothiadiazol-4-ylsulfonyl)aMino]-2-thienyl]carbonyl]-
Formula:
C17H19N7O5S3
Inquiry
COMPUTED DESCRIPTORS
| Molecular Weight | 497.6 g/mol |
|---|---|
| XLogP3 | 1 |
| Hydrogen Bond Donor Count | 5 |
| Hydrogen Bond Acceptor Count | 11 |
| Rotatable Bond Count | 10 |
| Exact Mass | 497.06098025 g/mol |
| Monoisotopic Mass | 497.06098025 g/mol |
| Topological Polar Surface Area | 268 Ų |
| Heavy Atom Count | 32 |
| Formal Charge | 0 |
| Complexity | 818 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 1 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
EG00229 is a member of the class of thiophenes that is thiophene substituted by a carbonyl-L-arginine and (2,1,3-benzothiadiazole-4-sulfonyl)amino groups at positions 2 and 3. It is an inhibitor of the neuropilin-1 and VEGF-A interaction and a potential anti-cancer agent. It has a role as an antineoplastic agent, a neuropilin receptor antagonist and an angiogenesis inhibitor. It is a benzothiadiazole, a sulfonamide, a member of thiophenes, a secondary carboxamide, a L-arginine derivative and a dicarboxylic acid monoamide.