L-2-Aminoadipic acid
Synonym(s):(S)-2-Aminohexanedioic acid;L -Homoglutamic acid;Aad
- CAS NO.：1118-90-7
- Empirical Formula: C6H11NO4
- Molecular Weight: 161.16
- MDL number: MFCD00002636
- EINECS: 601-134-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 04:53:45
What is L-2-Aminoadipic acid?
Chemical properties
WHITE SOLID
The Uses of L-2-Aminoadipic acid
L-2-Aminoadipic acid is an important raw material and intermediate used in organic synthesis, pharmaceuticals and agrochemicals.
The Uses of L-2-Aminoadipic acid
An inhibitor of ischemic glutamate release
What are the applications of Application
L-α-Aminoadipic acid is an inhibitor of ischemic glutamate release
Definition
ChEBI: The L-enantiomer of 2-aminoadipic acid.
General Description
L-2-Aminoadipic acid/α-aminoadipate is a gliotoxin and is a structural analog of glutamine. It is generated by the catabolism of lysine saccharopine (SAC)/pipecolic acid (PIP) pathways.
Biochem/physiol Actions
L-2-Aminoadipic acid inhibits glutamine synthetase and γ-glutamylcysteine synthetase. It modulates glucose metabolism and is present in higher levels in diabetic patients. L-2-Aminoadipic acid plays a key role in suppressing autophagy in C2C12 myotubes.
Properties of L-2-Aminoadipic acid
| Melting point: | 203-205 °C (dec.)(lit.) |
| Boiling point: | 287.44°C (rough estimate) |
| alpha | 22 º (c=2, 5 N HCl 25 ºC) |
| Density | 1.3482 (rough estimate) |
| refractive index | 1.4230 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | 1N HCl: 10 mg/ml; PBS (pH 7.2): 0.5 mg/ml |
| pka | 2.49±0.24(Predicted) |
| form | Solid |
| color | White |
| Water Solubility | Soluble in 1N HCl (50 mg/ml) and water (slightly). |
| BRN | 1724348 |
| CAS DataBase Reference | 1118-90-7(CAS DataBase Reference) |
Safety information for L-2-Aminoadipic acid
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for L-2-Aminoadipic acid
| InChIKey | OYIFNHCXNCRBQI-BYPYZUCNSA-N |
New Products
2-(2-Chlorophenyl)glycine Propiolic Acid 1-(3-Hydroxy-4-methoxyphenyl)-2-nitroethene (±)-amino(2-fluorophenyl)acetic acid trans-3-Benzyloxy-4-methoxy-beta-nitrostyrene 1-Pentadecanol 4-(4-Αminophenyl)-3-Morpholinone 3-Morpholino-1-(4-(2-oxopiperidin-1-yl) phenyl)-5,6-dihyropyridin-2-(1H)-one 1-(4-Aminophenyl)-3-morpholino-5,6-dihydropyridin-2(1H)-one N-cyanoacetylurethane 1H-IndazoleRelated products of tetrahydrofuran
You may like
-
L-2-Aminoadipic acid,97% 1118-90-7 99%View Details
1118-90-7 -
L-2-Aminoadipic Acid CAS 1118-90-7View Details
1118-90-7 -
L-2-Aminoadipic acid CAS 1118-90-7View Details
1118-90-7 -
L-2-Aminoadipic acid 98% CAS 1118-90-7View Details
1118-90-7 -
L-2-Aminoadipic acid 95.00% CAS 1118-90-7View Details
1118-90-7 -
L-2-Aminoadipic acid 98% (HPLC) CAS 1118-90-7View Details
1118-90-7 -
L-2-Aminoadipic acid CAS 1118-90-7View Details
1118-90-7 -
40216-83-9 trans-4-Hydroxy-L-proline methyl ester hydrochloride 98+View Details
40216-83-9
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.