JP1302
- CAS NO.：80259-18-3
- Empirical Formula: C24H24N4
- Molecular Weight: 368.47
- MDL number: MFCD10565599
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-10-29 15:43:00
What is JP1302?
The Uses of JP1302
JP 1302 Dihydrochloride is an α2-adrenoceptor blocker and can be used for the treatment or prevention of nephropathy.
What are the applications of Application
JP 1302 dihydrochloride is a selective α2C-AR
Biological Activity
α 2C -adrenoceptor antagonist that displays ~ 50-fold selectivity over other α 2 -adrenoceptor subtypes (K i values are 28, 1470, 1700 and 3150 nM for human α 2C , α 2B , α 2D and α 2A subtypes respectively). Potently antagonizes adrenalin-stimulated 35 GTP γ S binding in vitro (K B = 16 nM) and produces antidepressant and antipsychotic-like effects in vivo .
Properties of JP1302
| Boiling point: | 550.9±50.0 °C(Predicted) |
| Density | 1.227±0.06 g/cm3(Predicted) |
| storage temp. | Desiccate at -20°C |
| pka | 9.03±0.10(Predicted) |
| Water Solubility | <44.14mg/ml in Water |
Safety information for JP1302
Computed Descriptors for JP1302
New Products
Methyl 2-hydroxy-3-nitrobenzoate 1,3-Diethyl-1,3-Diphenylurea 2,4-dihydroxybenzaldehyde 3-(4-morpholinophenylamino)-5-amino-1H-pyrazole-4-carbonitrile Methyl 2-methylquinoline-6-carboxylate 2-((4-morpholinophenylamino) (methylthio) methylene) malononitrile 1,3-Di Iodo Benzene Methyl 2-oxo-2,3-dihydrobenzo[d]oxazole-7-carboxylate 4-(2-Aminoethyl)-7-hydroxy-2H-chromoen-2-one 3-Hydroxy-4-nitrobromobenzene 2-Ethyl-1,4-diaminobenzene 2-Ethylhexyl 4-aminobenzoate Thio AcetamideRelated products of tetrahydrofuran
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