JM 221
- CAS NO.：129551-91-3
- Empirical Formula: C8H14Cl2O4Pt.C6H13N.H3N
- Molecular Weight: 556.387
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-03-31 09:12:57
What is JM 221?
Description
JM-221 is a novel platinum(IV) dicarboxylate complex exhibiting enhanced cytotoxicity in human ovarian carcinoma cell line when compared to Cisplatin. Comparison with platinum accumulation from Cisplatin suggests that the increased cytotoxicity of JM-221 may be related_x000D_ to increased accumulation within the cell. JM-221 is more lipophilic than Cisplatin, which may account for improved uptake in Cisplatin resistant cells.
Safety information for JM 221
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