ISOMITRAPHYLLINE

Synonym(s):Ajmalicine oxindole A

CAS NO.：4963-01-3
Empirical Formula: C21H24N2O4
Molecular Weight: 368.43
MDL number: MFCD03788776
SAFETY DATA SHEET (SDS)
Update Date: 2026-01-05 11:31:08

What is ISOMITRAPHYLLINE?

Description

This Mitragyna alkaloid has been isolated from the leaves of M. speciosa Korth by Beckett and his colleagues. It is an amorphous solid which cannot be obtained crystalline. The base may be characterized as the picrate which forms pale yellow needles from MeOH, m.p. 223°C (dec.). A methylgroup, a methoxycarbonyl group and one imino group are present. The second nitrogen atom is tertiary.

The Uses of ISOMITRAPHYLLINE

Isomitraphylline is an oxoindole alkaloid derivied from amazonian plants and maintain medicinal benefits. Used in the treatment of ulcers, arthritis, etc.

References

Beckett et al., J. Pharm. Pharmacol., 17,753 (1965) Beckett et ai., Planta Med., 14, 266 (1966) Structure: Finch, Taylor., J. Amer. Chem. Soc., 84,3871 (1962) Prepara tion: Seaton et al., Can. J. Chem., 38, 1035 (1960)

Properties of ISOMITRAPHYLLINE

Boiling point:	555.2±50.0 °C(Predicted)
Density	1.33±0.1 g/cm3(Predicted)
storage temp.	-20°C
pka	13.56±0.60(Predicted)

Safety information for ISOMITRAPHYLLINE

Signal word	Danger
Pictogram(s)	Skull and Crossbones Acute Toxicity GHS06
GHS Hazard Statements	H300:Acute toxicity,oral
Precautionary Statement Codes	P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P405:Store locked up. P501:Dispose of contents/container to..…