Isofraxidin
Synonym(s):6,8-Dimethoxyumbelliferone;7-Hydroxy-6,8-dimethoxychromen-2-one;7-Hydroxy-6,8-dimethoxycoumarin
- CAS NO.：486-21-5
- Empirical Formula: C11H10O5
- Molecular Weight: 222.19
- MDL number: MFCD00221757
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-02-25 19:46:50
What is Isofraxidin?
The Uses of Isofraxidin
Isofraxidin is used as an anti-inflammatory compound. Inhibits pro-inflammatory cytokines.
Definition
ChEBI: Isofraxidin is a hydroxycoumarin.
Properties of Isofraxidin
| Melting point: | 145～147℃ |
| Boiling point: | 452.1±45.0 °C(Predicted) |
| Density | 1.358±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO: 250 mg/mL (1125.16 mM) |
| form | Solid |
| form | neat |
| pka | 7.92±0.20(Predicted) |
| color | Yellow to brown |
| BRN | 202652 |
| CAS DataBase Reference | 486-21-5(CAS DataBase Reference) |
Safety information for Isofraxidin
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Corrosion Corrosives GHS05  Skull and Crossbones Acute Toxicity GHS06  Health Hazard GHS08 |
| GHS Hazard Statements |
H226:Flammable liquids H290:Corrosive to Metals H314:Skin corrosion/irritation H330:Acute toxicity,inhalation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H336:Specific target organ toxicity,single exposure; Narcotic effects H361:Reproductive toxicity H371:Specific target organ toxicity, single exposure H372:Specific target organ toxicity, repeated exposure H373:Specific target organ toxicity, repeated exposure H412:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. P202:Do not handle until all safety precautions have been read and understood. P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P234:Keep only in original container. P240:Ground/bond container and receiving equipment. P241:Use explosion-proof electrical/ventilating/lighting/…/equipment. P242:Use only non-sparking tools. P243:Take precautionary measures against static discharge. P260:Do not breathe dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P271:Use only outdoors or in a well-ventilated area. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P284:Wear respiratory protection. P363:Wash contaminated clothing before reuse. P390:Absorb spillage to prevent material damage. P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P370+P378:In case of fire: Use … for extinction. P405:Store locked up. P406:Store in corrosive resistant/… container with a resistant inner liner. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P403+P235:Store in a well-ventilated place. Keep cool. |
Computed Descriptors for Isofraxidin
New Products
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