HYDROQUINIDINE
Synonym(s):(9S)-10,11-Dihydro-6′-methoxycinchonan-9-ol;Dihydroquinidine;Hydroquinidine
- CAS NO.：1435-55-8
- Empirical Formula: C20H26N2O2
- Molecular Weight: 326.43
- MDL number: MFCD00135599
- EINECS: 215-862-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-06-24 21:05:35
What is HYDROQUINIDINE?
Chemical properties
Solid
The Uses of HYDROQUINIDINE
antiarrhythmic, antimalarial
What are the applications of Application
A useful biochemical for proteomics research
Purification Methods
It is slightly soluble in Et2O and H2O but readily soluble in hot EtOH. [Heidelberger & Jacobs J Am Chem Soc 41 826 1919, King J Chem Soc 523 1946.] The hydrochloride has m 273-274o, [] 26D +184o (c 1.3, MeOH) and is very soluble in MeOH and CHCl3, but less soluble in H2O, EtOH and still less soluble in dry Me2CO. [Kyker & Lewis J Biol Chem 157 707 1945, Emde Helv Chim Acta 15 557 1932, Beilstein 23/13 V 340.]
Properties of HYDROQUINIDINE
| Melting point: | 169-170 °C(lit.) |
| Boiling point: | 464.47°C (rough estimate) |
| alpha | 226 º (C=2 IN ETOH) |
| Density | 1.1117 (rough estimate) |
| refractive index | 1.6800 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | chloroform: 0.1 g/mL, clear |
| pka | 12.80±0.20(Predicted) |
| form | A crystalline solid |
| color | White to off-white |
| optical activity | [α]25/D +226°, c = 2 in ethanol |
| Merck | 13,4831 |
| BRN | 91441 |
| CAS DataBase Reference | 1435-55-8(CAS DataBase Reference) |
| NIST Chemistry Reference | Hydroquinidine(1435-55-8) |
Safety information for HYDROQUINIDINE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P501:Dispose of contents/container to..… |
Computed Descriptors for HYDROQUINIDINE
| InChIKey | LJOQGZACKSYWCH-LHFMAAMQSA-N |
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