HOOCCH2CH2-PEG16-CH2CH2COOH
- CAS NO.：2226897-74-9
- Empirical Formula: C38H74O21
- Molecular Weight: 866.98
- MDL number: MFCD21363297
- Update Date: 2025-07-16 09:55:30
What is HOOCCH2CH2-PEG16-CH2CH2COOH?
Biological Activity
Bis-PEG17-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Properties of HOOCCH2CH2-PEG16-CH2CH2COOH
| form | Solid |
| color | Off-white to light yellow |
Safety information for HOOCCH2CH2-PEG16-CH2CH2COOH
Computed Descriptors for HOOCCH2CH2-PEG16-CH2CH2COOH
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