Acid-PEG5-t-butyl ester
- CAS NO.：1309460-29-4
- Empirical Formula: C18H34O9
- Molecular Weight: 394.46
- MDL number: MFCD18916989
- Update Date: 2026-03-18 11:52:23
What is Acid-PEG5-t-butyl ester?
Description
Acid-PEG5-t-butyl ester is a PEG linker containing a t-butyl protected carboxyl group with a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
Properties of Acid-PEG5-t-butyl ester
| Boiling point: | 495.2±45.0 °C(Predicted) |
| Density | 1.109±0.06 g/cm3(Predicted) |
| solubility | Soluble in Water, DMSO, DCM, DMF |
| pka | 4.28±0.10(Predicted) |
| form | Liquid |
| color | Colorless to light yellow |
Safety information for Acid-PEG5-t-butyl ester
Computed Descriptors for Acid-PEG5-t-butyl ester
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