Bisphenol AF
Synonym(s):2,2-Bis(4-hydroxyphenyl)hexafluoropropane;4,4′-(Hexafluoroisopropylidene)diphenol;Bisphenol AF;Hexafluorobisphenol A
- CAS NO.：1478-61-1
- Empirical Formula: C15H10F6O2
- Molecular Weight: 336.23
- MDL number: MFCD00000439
- EINECS: 216-036-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-10 10:27:19
What is Bisphenol AF?
Chemical properties
white to off-white powder
The Uses of Bisphenol AF
Hexafluorobisphenol A acts as an endocrine-disrupting chemical (EDC), activating estrogen through the estrogen receptor ERα. It is a full agonist for the estrogen receptor.
The Uses of Bisphenol AF
fluororubber crosslinking agent
The Uses of Bisphenol AF
Hexafluorobisphenol A mainly is used for fluorine rubber vulcanization accelerator FF34 with fluorine rubber, vulcanized permanent deformation resistance, tensile strength is high; but also can be used as pharmaceutical intermediates.
Definition
ChEBI: An organofluorine compound that is bisphenol A with its methyl hydrogens replaced by fluorines.
Hazard
Moderately toxic by ingestion.
Flammability and Explosibility
Not classified
Properties of Bisphenol AF
| Melting point: | 160-163 °C(lit.) |
| Boiling point: | 400°C |
| Density | 1.3837 (estimate) |
| vapor pressure | 0Pa at 20℃ |
| Flash point: | >100°C |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | neat |
| pka | 8.74±0.10(Predicted) |
| color | White to Pale Beige |
| Water Solubility | Insoluble in water. |
| BRN | 1891568 |
| CAS DataBase Reference | 1478-61-1(CAS DataBase Reference) |
| EPA Substance Registry System | Phenol, 4,4'-[2,2,2-trifluoro-1-(trifluoromethyl)ethylidene]bis- (1478-61-1) |
Safety information for Bisphenol AF
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Bisphenol AF
| InChIKey | ZFVMWEVVKGLCIJ-UHFFFAOYSA-N |
Bisphenol AF manufacturer
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