4,4'-Dihydroxydiphenylmethane

Synonym(s):4,4′-Methylenediphenol;Bis(4-hydroxyphenyl)methane;Bisphenol F

CAS NO.：620-92-8
Empirical Formula: C13H12O2
Molecular Weight: 200.23
MDL number: MFCD00002385
EINECS: 210-658-2
SAFETY DATA SHEET (SDS)
Update Date: 2026-09-12 18:54:17

4,4'-Dihydroxydiphenylmethane Structural

What is 4,4'-Dihydroxydiphenylmethane?

Chemical properties

Off-White to Light Pink Solid

The Uses of 4,4'-Dihydroxydiphenylmethane

4,4'-Dihydroxydiphenylmethane, is also used as a bisphenol derivative with antioxidant activities. Bisphenol F has been reported to exhibit estrogen agonistic properties. Bisphenol F is used to make epoxy resins and coatings for various applications, such as lacquers, varnishes, liners, adhesives, plastics, water pipes, dental sealants, and food packaging.

The Uses of 4,4'-Dihydroxydiphenylmethane

Bisphenol F is a bisphenol derivative with antioxidant activities. Bisphenol F has been reported to exhibit estrogen agonistic properties.

Definition

ChEBI: A bisphenol that is methane in which two of the hydrogens have been replaced by 4-hydroxyphenyl groups.

General Description

Bisphenol F (BPF), an endocrine disrupting compound, is a bisphenol analog, widely used as an alternative to BPA in the production of consumer products. BPF is also used in a variety of industrial applications, including lacquer coatings in cans, food packaging, sealants, dental composites, etc.

Contact allergens

p,p-Bisphenol F is an allergenic component of phenol-formaldehyde resins resol-type.

Properties of 4,4'-Dihydroxydiphenylmethane

Melting point:	162-164 °C
Boiling point:	297.96°C (rough estimate)
Density	1.0907 (rough estimate)
refractive index	1.6110 (estimate)
storage temp.	Sealed in dry,Room Temperature
solubility	DMSO (Slightly), Methanol (Slightly)
form	neat
pka	9.91±0.10(Predicted)
form	Solid
color	Off-White to Light Red
Water Solubility	It is soluble in ethanol, ether, chloroform, alkali; slightly soluble in DMSO, insoluble in carbon disulfide and water.
BRN	2049425
CAS DataBase Reference	620-92-8(CAS DataBase Reference)
EPA Substance Registry System	Phenol, 4,4'-methylenebis- (620-92-8)

Safety information for 4,4'-Dihydroxydiphenylmethane

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.