GUANYLIN (RAT)
- CAS NO.：144940-98-7
- Empirical Formula: C60H90N16O22S4
- Molecular Weight: 1515.71
- MDL number: MFCD00187932
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
What is GUANYLIN (RAT)?
Description
Guanylin is a peptide hormone consisting of 15 aa residues that binds to the guanylyl cyclase C (GUCY2C) receptor to produce cGMP. It plays an important role in regulating ion and water transport and maintaining epithelial homeostasis in the intestine and kidney. Eel renoguanylin (Rgn) is more similar to GN than to uroguanylin (UGN), and thus is described here.
The Uses of GUANYLIN (RAT)
Guanylin (rat, mouse) is an endogenous intestinal guanylyl cyclase activator.
What are the applications of Application
Guanylin (rat, mouse) is a gastrointestinal peptide hormone and intestinal guanyl cyclase C activator.
Clinical Use
Two GN/UGN agonists, linaclotide and plecanatide, have recently been approved in the United States, European Union, Japan, and other countries to treat irritable bowel syndrome and chronic constipation. They have also been approved in the United States to treat chronic idiopathic constipation and irritable bowel syndrome with constipation, respectively.
Properties of GUANYLIN (RAT)
| storage temp. | −20°C |
| form | solid |
| color | white |
| Water Solubility | Soluble in water |
Safety information for GUANYLIN (RAT)
Computed Descriptors for GUANYLIN (RAT)
New Products
Paroxetine Impurity G/Paroxetine Related Compound E 1-Aminocyclopentane carbonitrile (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid N,N CARBONYL DIIMIDAZOLE 2-Amino-5-bromo-4-(trifluoromethyl)pyridine（RM for Indian lab) Benzyl (3R,4S)-3-(2-bromoacetyl)-4-ethylpyrrolidine-1-carboxylate (R)-1-Benzyl-3-pyrrolidinecarbonitrile Betahistine EP Impurity C Cyclobenzaprine N-oxide/Citalopram Related Compound E Chlorthalidone Impurity I Carbamazepine EP Impurity G Sumatriptan Succinate USP Related Compound C 2,2'-(5-methyl-1,3-phenylene)-di(2-Methylpropionitrile) 4-Fluorothiophenol 1-methyl amino-2,4-dinitro benzene 5-Methyl-1,3-benzenediacetonitrile (R)-BoroLeu-(+)-Pinanediol-CF3COOH 4-(5-amino-1-methyl-1h-benzoimidazol-2-yl)-butyric acid isopropyl ester. 4-Bromo Benzylcyanide 3-Hydroxypropionitrile valeronitrile 3,4 Dimethoxy Benzylcyanide 3-chlorobenzyl cyanide 2-Chloro BenzylcyanideRelated products of tetrahydrofuran
![GUANYLIN [3-(125I)TYR9], RAT](https://img.chemicalbook.in/StructureFile/ChemBookStructure2/GIF/CB3735785.gif)
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