GTP-GAMMA-S SODIUM SALT
Synonym(s):GTP
- CAS NO.：37589-80-3
- Empirical Formula: C10H16N5O13P3S
- Molecular Weight: 539.25
- MDL number: MFCD03791271
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-01-27 09:38:02
What is GTP-GAMMA-S SODIUM SALT?
The Uses of GTP-GAMMA-S SODIUM SALT
GTP-γ-S has been used:
- in G-Protein activation assay to assess the functionality of protease-activated receptor 4 (PAR4)
- in fluorimetric guanine nucleotide exchange assay of G protein alpha subunits (Gα)
- to monitor the Rac family small guanosine triphosphatase (GTPase) 2 (Rac2)-stimulated activity of phospholipase Cγ2 mutants
Definition
ChEBI: Guanosine 5'-[gamma-thio]triphosphate is a nucleoside triphosphate analogue. It is functionally related to a GTP.
General Description
Guanosine 5′-O-(3-thiotriphosphate), tetralithium salt (GTP-γ-S) is a non-hydrolysable analog of GTP. It is an inhibitor of phosphodiesterase in photoreceptors.
Biochem/physiol Actions
Guanosine 5′-O-(3-thiotriphosphate) (GTP-γ-S) activates guanine-nucleotide-binding proteins and is slowly hydrolyzed enzymatically. It inhibits guanosine triphosphatase (GTPases) more potently than guanosine triphosphate (GTP),
Properties of GTP-GAMMA-S SODIUM SALT
| Density | 2.68±0.1 g/cm3(Predicted) |
| storage temp. | -20°C (-15°C to -25°C) |
| form | solution (deep frozen) |
| pka | 0.67±0.50(Predicted) |
Safety information for GTP-GAMMA-S SODIUM SALT
Computed Descriptors for GTP-GAMMA-S SODIUM SALT
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