GSK 2330672
- CAS NO.：1345982-69-5
- Empirical Formula: C28H38N2O7S
- Molecular Weight: 546.68
- MDL number: MFCD28386358
- EINECS: 604-604-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-12-05 14:33:18
What is GSK 2330672?
Description
GSK2330672 is an inhibitor of the apical sodium-dependent bile acid transporter (ASBT; IC50s = 42, 2.1, and 1.9 nM for human, mouse, and rat ASBT, respectively). In vivo, GSK2330672 (0.05 mg/kg) stimulates fecal bile acid secretion, reduces hemoglobin A1c (HbA1c) and plasma glucose levels, and increases total GLP-1 and plasma insulin in Zucker diabetic fatty (ZDF) rats.
Properties of GSK 2330672
| Boiling point: | 730.8±60.0 °C(Predicted) |
| Density | 1.218±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMF: 5 mg/ml; DMSO: 2 mg/ml; PBS (pH 7.2): 0.2 mg/ml |
| form | A crystalline solid |
| pka | 3.27±0.10(Predicted) |
| color | White to off-white |
Safety information for GSK 2330672
Computed Descriptors for GSK 2330672
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