glybuzole
- CAS NO.：1492-02-0
- Empirical Formula: C12H15N3O2S2
- Molecular Weight: 297.401
- MDL number: MFCD00724711
- EINECS: 2160812
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-21 10:31:43
What is glybuzole?
Originator
Gludease,Kyowa Hakko,Japan,1972
Definition
ChEBI: Glybuzole is an organic molecular entity.
Manufacturing Process
15.7 g of 2-amino-5-tert-butyl-1,3,4-thiadiazole (0.1 mol) and 17.6 g of benzene sulfonyl chloride (0.1 mol) were dissolved in 150 ml dry pyridine and heated over steam for 4 hr. The pyridine was removed by distillation under reduced pressure and the residue treated with 50 ml 2N HCl. The solid product, MP 162° to 163°C. was filtered off and recrystallized once from benzene and twice from 50% aqueous EtOH.
Therapeutic Function
Oral hypoglycemic
Properties of glybuzole
| Melting point: | 163° |
| Boiling point: | 449.4±28.0 °C(Predicted) |
| Density | 1.3286 (rough estimate) |
| refractive index | 1.6560 (estimate) |
| pka | 6.49±0.40(Predicted) |
Safety information for glybuzole
Computed Descriptors for glybuzole
New Products
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