(Gly1,Ser3·22,Gln4·34,Thr6,Arg19,Tyr21,Ala23·31,Aib32)-Pancreatic Polypeptide (human)
- CAS NO.：313988-89-5
- Empirical Formula: C183H281N57O54S2
- Molecular Weight: 4207.66874
- MDL number: MFCD03456490
- Update Date: 2026-04-24 14:58:14
What is (Gly1,Ser3·22,Gln4·34,Thr6,Arg19,Tyr21,Ala23·31,Aib32)-Pancreatic Polypeptide (human)?
Biological Activity
cPP1-7,NPY19-23,Ala31,Aib32,Gln34 is a potent and selective neuropeptide YY5 receptor agonist with IC50 of 0.24 nM for hY5 receptor binding. It increases dietary intake.
in vitro
cPP1-7,NPY19-23,Ala31,Aib32,Gln34 has IC 50 s of 530 nM, >500 nM , 51 nM for binding to the hY 1 , hY 4 , hY 2 receptors.
in vivo
cPP1-7,NPY19-23,Ala31,Aib32,Gln34 induces a high amount of food intake in a dose-dependent manner in adult male rats weighing 340-400 g.
Properties of (Gly1,Ser3·22,Gln4·34,Thr6,Arg19,Tyr21,Ala23·31,Aib32)-Pancreatic Polypeptide (human)
| storage temp. | Store at -20°C |
| solubility | Soluble to 1 mg/ml in 10% acetonitrile |
| form | Powder |
| color | White to off-white |
Safety information for (Gly1,Ser3·22,Gln4·34,Thr6,Arg19,Tyr21,Ala23·31,Aib32)-Pancreatic Polypeptide (human)
Computed Descriptors for (Gly1,Ser3·22,Gln4·34,Thr6,Arg19,Tyr21,Ala23·31,Aib32)-Pancreatic Polypeptide (human)
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