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Glutaurine

Glutaurine Structural

What is Glutaurine?

The Uses of Glutaurine

Glutaurine has been observed to display antiepileptic effects with anti-amnesia properties. Mimics anxiolytic drug Diazepam (D416855).

Definition

ChEBI: Glutaurine is a dipeptide resulting from the formal condensation of the amino group of taurine with the gamma-carboxy group of L-glutamic acid. It was initially found in the parathyroid in 1980 and later in the brain of mammals. It has a role as a mouse metabolite, a mammalian metabolite, a human metabolite, an anticonvulsant, an anxiolytic drug and a hormone. It is a L-glutamine derivative, a sulfonic acid and a dipeptide. It is functionally related to a taurine. It is a tautomer of a glutaurine zwitterion.

Properties of Glutaurine

Melting point: 223-226 °C
Density  1.520±0.06 g/cm3(Predicted)
storage temp.  under inert gas (nitrogen or Argon) at 2–8 °C
solubility  DMF: insol; DMSO: 1 mg/ml; Ethanol: insol; PBS (pH 7.2): 5 mg/ml
form  A solid
pka 1.40±0.50(Predicted)
Water Solubility  Water : 125 mg/mL (491.62 mM; Need ultrasonic)

Safety information for Glutaurine

Computed Descriptors for Glutaurine

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