GGTI-2417
- CAS NO.：501010-05-5
- Empirical Formula: C24H33N5O4
- Molecular Weight: 455.55
- MDL number: MFCD25976817
- Update Date: 2026-04-21 11:20:27
What is GGTI-2417?
Description
GGTI2417 is a potent and selective Geranylgeranyltransferase I inhibitor that targets RalB to inhibit anchorage-dependent growth and induce apoptosis and RalA to inhibit anchorage-independent growth. By expressing farnesylated, GGTI-resistant RalA and RalB in Cos7 cells and human pancreatic MiaPaCa2 cancer cells followed by GGTI-2417 treatment, it was demonstrated that farnesylated RalB, but not RalA, confers resistance to the proapoptotic and anti-anchorage-dependent growth effects of GGTI-2417.
Safety information for GGTI-2417
New Products
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