GD2-GANGLIOSIDE
Synonym(s):GalNAcβ1,4(Neu5Acα2,8)(Neu5Acα2,03)Galβ1,4Glcβ1,1ʹ Ceramide;Ganglioside GD₂, Disialo, Human Brain - CAS 65988-71-8 - Calbiochem
- CAS NO.:65988-71-8
- Empirical Formula: C74H134N4O32
- Molecular Weight: 1591.86336
- MDL number: MFCD00131133
- Update Date: 2026-04-24 14:58:55
What is GD2-GANGLIOSIDE?
Chemical properties
lyophilized powder
The Uses of GD2-GANGLIOSIDE
Disialoganglioside-GD2 from bovine brain has been used:
- in the ganglioside- enzyme-linked immunosorbent assay (ELISA)
- in capture ELISA with anti-GD2 antibody (ch14.18)
- as a control to test its effect on reactivating autophagy in primary fibroblasts
What are the applications of Application
Ganglioside GD2, Disialo, Human Brain is a ganglioside marker of various cell types
General Description
Disialoganglioside GD2 is a cell surface-associated glycosphingolipid, which comprises sialic acid moiety and is regarded as a carbohydrate antigen.. It is expressed in the skin melanocytes, central and peripheral nervous system.
Biochem/physiol Actions
Disialoganglioside GD2 is expressed in neuroblastoma, melanoma and small cell lung cancer. It is an immunotherapeutic target and is also regarded as a tumor-associated antigen. GD2 may favor cell migrationin tumors by promoting cell growth, as well as extracellular matrix component attachment.
Properties of GD2-GANGLIOSIDE
| storage temp. | −20°C |
| form | lyophilized powder |
Safety information for GD2-GANGLIOSIDE
Computed Descriptors for GD2-GANGLIOSIDE
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