Ftivazide
- CAS NO.：149-17-7
- Empirical Formula: C14H13N3O3
- Molecular Weight: 271.27
- MDL number: MFCD00033812
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-24 14:58:06
What is Ftivazide?
The Uses of Ftivazide
Isonicotinic Acid Vanillylidenehydrazide exhibits anti-mycobacterial activity against Mycobacterium tuberculosis and anti-microbial activity against Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Candida albicans, and Aspergillus niger.Also, it is derived from Isoniazid (I821450), which is an antibiotic for treatment of Mycobacterium tuberculosis, inhibits mycolic acid biosynthesis. Metabolized by hepatic N-acetyltransferase (NAT) and cytochrome P450 2E1 (CYP2E1) to form hepatotoxins. Selectively induces expression of CYP2E1. Reversibly inhibits CYP2C19 and CYP3A4 activities, and mechanistically inactivates CYP1A2, CYP2A6, CYP2C19 and CYP3A4 at clinically relevant concentrations. Antibacterial (tuberculostatic).
Definition
ChEBI: Ftivazide is a member of phenols and a member of methoxybenzenes.
Properties of Ftivazide
| Melting point: | 219-220 °C |
| Boiling point: | 414.36°C (rough estimate) |
| Density | 1.2122 (rough estimate) |
| refractive index | 1.5700 (estimate) |
| pka | 8.65±0.35(Predicted) |
Safety information for Ftivazide
Computed Descriptors for Ftivazide
New Products
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