folescutol
- CAS NO.：15687-22-6
- Empirical Formula: C14H15NO5
- Molecular Weight: 277.27
- EINECS: 239-783-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-04 17:34:34
What is folescutol ?
Originator
Folescutol ,hydrochloride
Definition
ChEBI: Folescutol is a hydroxycoumarin.
Manufacturing Process
A solution 35.6 g of 4-chlormethyl-6,7-dihydroxycoumarin and 27.3 g of morpholine in 4.5 L methyl ethyl ketone was refluxed for 9 hours. On cooling the morpholine hydrochloride was deleted. Methyl ethyl ketone was evaporated in vacuum. The solid product was mixed with 500 ml of water and dried in vacuum with P2O5. Yield of crude 6,7-dihydroxy-4(morpholinomethyl)coumarin is 41.5 g. After recrystallization from ethanol was obtained 6,7-dihydroxy-4-(morpholinomethyl)coumarin with M.P. 232°C.
In practice it is usually used as hydrochloride.
Therapeutic Function
Capillary protective
Properties of folescutol
| Melting point: | 232° |
| Boiling point: | 529.7±50.0 °C(Predicted) |
| Density | 1.428±0.06 g/cm3(Predicted) |
| pka | 7.80±0.20(Predicted) |
Safety information for folescutol
Computed Descriptors for folescutol
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