FERROUS ASCORBATE

Synonym(s):L-(+)-Ascorbic acid iron(II) salt;Ferrous ascorbate;Vitamin C iron(II) salt

CAS NO.：24808-52-4
Empirical Formula: C18H21FeO18
Molecular Weight: 581.19
MDL number: MFCD16652607
EINECS: 246-469-7
SAFETY DATA SHEET (SDS)
Update Date: 2023-05-25 18:01:22

What is FERROUS ASCORBATE?

Absorption

The efficiency of absorption depends on the salt form, the amount administered, the dosing regimen and the size of iron stores. Subjects with normal iron stores absorb 10% to 35% of an iron dose. Those who are iron deficient may absorb up to 95% of an iron dose.

Toxicity

Acute iron overdosage can be divided into four stages. In the first stage, which occurs up to six hours after ingestion, the principal symptoms are vomiting and diarrhea. Other symptoms include hypotension, tachycardia and CNS depression ranging from lethargy to coma. The second phase may occur at 6-24 hours after ingestion and is characterized by a temporary remission. In the third phase, gastrointestinal symptoms recur accompanied by shock, metabolic acidosis, coma, hepatic necrosis and jaundice, hypoglycemia, renal failure and pulmonary edema. The fourth phase may occur several weeks after ingestion and is characterized by gastrointestinal obstruction and liver damage. In a young child, 75 milligrams per kilogram is considered extremely dangerous. A dose of 30 milligrams per kilogram can lead to symptoms of toxicity. Estimates of a lethal dosage range from 180 milligrams per kilogram and upwards. A peak serum iron concentration of five micrograms or more per ml is associated with moderate to severe poisoning in many.

Description

§184.1307a(a) Ferrous ascorbate (CAS No. 14356-17-5) is a reaction product of ferrous hydroxide and ascorbic acid. It is a blue violet product containing 16% iron.

Chemical properties

Blue-violet solid.

The Uses of FERROUS ASCORBATE

Ferrous Ascorbate is a nutrient supplement, blue-violet in color, containing 16% iron. it is a reaction product of ferrous hydroxide and ascorbic acid. it may be used in infant formula.

The Uses of FERROUS ASCORBATE

Food additive.

Indications

Used in preventing and treating iron-deficiency anemia.

Hazard

A nuisance dust.

Pharmacokinetics

The major activity of supplemental iron is in the prevention and treatment of iron deficiency anemia. Iron has putative immune-enhancing, anticarcinogenic and cognition-enhancing activities.