Fananserin
- CAS NO.：127625-29-0
- Empirical Formula: C23H24FN3O2S
- Molecular Weight: 425.52
- MDL number: MFCD00866648
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-17 09:03:53
What is Fananserin?
The Uses of Fananserin
Fananserin is an antagonist of 5-HT2A.
The Uses of Fananserin
Antipsychotic.
What are the applications of Application
Fananserin is an antagonist of 5-HT2A
Definition
ChEBI: LSM-2183 is a sulfonic acid derivative and a member of naphthalenes.
Biological Activity
5-HT 2A receptor antagonist that also displays high affinity at D 4 receptors (K i values are 0.26, 2.93, 25, 38, 70 and 726 nM for 5-HT 2A , D 4 , H 1 , α 1 , 5-HT 1A and D 2 receptors respectively). Inhibits inositol phosphate formation evoked by 5-HT in vitro (IC 50 = 7.76 nM) and antagonizes mescaline-induced head twitches in vivo .
Properties of Fananserin
| Melting point: | 95-97 °C(Solv: acetonitrile (75-05-8)) |
| Boiling point: | 641.1±65.0 °C(Predicted) |
| Density | 1.331±0.06 g/cm3(Predicted) |
| storage temp. | Store at RT |
| solubility | Soluble to 100 mM in DMSO |
| form | Powder |
| pka | 7.31±0.10(Predicted) |
Safety information for Fananserin
Computed Descriptors for Fananserin
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