ethyl 1-benzyl-3-hydroxy-2(5H)-oxopyrrole-4-carboxylate
- CAS NO.：4450-98-0
- Empirical Formula: C14H15NO4
- Molecular Weight: 261.27
- MDL number: MFCD00179167
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:20:38
What is ethyl 1-benzyl-3-hydroxy-2(5H)-oxopyrrole-4-carboxylate?
Description
The human aldose reductase AKR1B1 is considered the rate limiting enzyme of the polyol pathway responsible for the conversion of glucose into sorbitol. It also acts as a highly efficient PGF2α synthase in response to interleukin-
The Uses of ethyl 1-benzyl-3-hydroxy-2(5H)-oxopyrrole-4-carboxylate
A highly specific aldose reductase inhibitor that has been shown to enhance HeLa cell sensitivity to chemotherapeutic drugs.
Definition
ChEBI: Ethyl 1-benzyl-3-hydroxy- 2-oxo[5H]pyrrole-4-carboxylate is a pyrroline and a carboxylic acid.
Properties of ethyl 1-benzyl-3-hydroxy-2(5H)-oxopyrrole-4-carboxylate
| Melting point: | 135-136 °C |
| Boiling point: | 479.8±45.0 °C(Predicted) |
| Density | 1.340±0.06 g/cm3(Predicted) |
| storage temp. | room temp |
| solubility | DMSO: ≥10mg/mL |
| form | white powder |
| pka | 4.50±1.00(Predicted) |
Safety information for ethyl 1-benzyl-3-hydroxy-2(5H)-oxopyrrole-4-carboxylate
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H318:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for ethyl 1-benzyl-3-hydroxy-2(5H)-oxopyrrole-4-carboxylate
New Products
Levothyroxine Impurity-F Montelukast EP Impurity-D/Montelukast USP Related Compound C Atorvastatin FXA Impurity/Atorvastatin Cyclic 6-Hydroxy Impurity Sodium Salt Isosulfan blue Keto N-Oxide Impurity Ivermectin Impurity F N-Nitroso des Methyl Tramadol/N-Nitroso-N-Desmethyl-Tramadol DL-beta-(3-Bromophenyl)alanine Tetrabutylammonium perchlorate N,O-Dimethylhydroxylamine hydrochloride (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid 2-Amino-5-bromo-4-(trifluoromethyl)pyridine（RM for Indian lab) N,N CARBONYL DIIMIDAZOLE (R)-BoroLeu-(+)-Pinanediol-CF3COOH 1,4-bis(methylsulfonyl)butane 4-(5-amino-1-methyl-1h-benzoimidazol-2-yl)-butyric acid isopropyl ester. 5-Methyl-1,3-benzenediacetonitrile 4-Fluorothiophenol 1-methyl amino-2,4-dinitro benzene CSA (DL-10-Camphorsulfonic Acid) 2-Hydroxy-4-methylnicotinic acid 3-iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine (2S)-1-((2S,3S)-3-(2-methylbutyl)-4-oxooxetan-2-yl)pentadecan-2-yl formylleucinate 1-(3,5-dichlorophenyl)-2,2,2-trifluoroethane-1-sulfonyl chloride S-(1-(3,5-dichlorophenyl)-2,2,2-trifluoroethyl) ethanethioateRelated products of tetrahydrofuran
You may like
-
EBPC CAS 4450-98-0View Details
4450-98-0 -
674783-97-2 98+View Details
674783-97-2 -
H-D-TRP(FOR)-OH HCL 98+View Details
367453-01-8 -
DL-beta-(3-Bromophenyl)alanine 117391-50-1 98+View Details
117391-50-1 -
49830-37-7 98+View Details
49830-37-7 -
3-Amino-3-(4-fluorophenyl)propanoic acid 98+View Details
325-89-3 -
1428243-26-8 98+View Details
1428243-26-8 -
1-aminocyclopentane carbonitrile, HCl 98+View Details
16195-83-8