cis-5,8,11,14,17-Eicosapentaenoic acid sodium salt

The Uses of cis-5,8,11,14,17-Eicosapentaenoic acid sodium salt

cis-5,8,11,14,17-Eicosapentaenoic acid sodium salt has been used:

• to study its effect on the pathology of lupus in drug-induced and spontaneous mouse models
• to pretreat mouse alveolar macrophages to study the effect/relationship between amiodarone and eicosapentaenoic acid (EPA) concerning the cytokine release
• to examine if pharmacological correction with EPA supplementation might restore autophagic flux and reduce renal lipotoxicity in mice

The Uses of cis-5,8,11,14,17-Eicosapentaenoic acid sodium salt

reduces thromboxane A2 production and platelet aggregation, inhibits 5-lipoxygenase and prevents arteriosclerosis.

What are the applications of Application

cis-5,8,11,14,17-Eicosapentaenoic acid sodium salt is an inhibitor of 5-LO

General Description

Eicosapentaenoic acid (EPA)/timnodonic acid is an omega-3 polyunsaturated fatty acid (PUFA). This long-chain fatty acid is mainly found in fish oil.

Biochem/physiol Actions

Eicosapentaenoic acid (EPA) possesses anti-hyperglycemic, anti-oxidant, anti-hyperlipidemic, and anti-inflammatory properties. It aids in improving vasoreactivity. EPA is capable of suppressing vascular smooth muscle proliferation. It ameliorates pulmonary hypertension by preventing Fyn kinase activity. EPA exhibits a beneficial effect on lipid metabolism. It is used to treat hypercholesterolemia and atherosclerosis.