15(S)-HEPE
- CAS NO.：86282-92-0
- Empirical Formula: C20H30O3
- Molecular Weight: 318.45
- MDL number: MFCD00065817
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-21 10:31:43
What is 15(S)-HEPE?
Description
15(S)-HEPE is a monohydroxy fatty acid. 15(S)-HEPE is biosynthesized from eicosapentaenoic acid (Item Nos. 90110 | 90110.1 | 21908) by 15-lipoxygenase (15-LO). Serum levels of 15(S)-HEPE are elevated in patients with asthma.
What are the applications of Application
15(S)-HEPE is an eicosapentaenoic acid-derived monohydroxy fatty acid
Definition
ChEBI: 15(S)-HEPE is a 15-HEPE that consists of (5Z,8Z,11Z,13E,17Z)-icosapentaenoic acid in which the 15-hydroxy group has S-configuration. It has a role as a human xenobiotic metabolite. It is a conjugate acid of a 15(S)-HEPE(1-). It is an enantiomer of a 15(R)-HEPE.
Properties of 15(S)-HEPE
| Boiling point: | 488.0±45.0 °C(Predicted) |
| Density | 0.997±0.06 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | 0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml |
| pka | 4.75±0.10(Predicted) |
Safety information for 15(S)-HEPE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 15(S)-HEPE
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![15(S)-HPEPE [1-14C]](https://img.chemicalbook.in/StructureFile/ChemBookStructure8/GIF/CB1270576.gif)
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