DU-14
- CAS NO.：186303-55-9
- Empirical Formula: C22H38N2O4S
- Molecular Weight: 426.61
- MDL number: MFCD19381840
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:26:45
What is DU-14?
Description
DU-14 (186303-55-9) inhibits steroid sulfatase (IC50=ca. 60 nM). Enhances learning and spatial memory in rats.1 Inhibits proliferation of human MCF-7 breast cancer cells.2
References
1) Johnson et al. (2000), The effect of steroid sulfatase inhibition on learning and spatial memory; Brain Res., 865 286 2) Selcer et al. (1997), Inhibition of estrone sulfatase and proliferation of human breast cancer cells by nonsteroidal (p-O-sulfamoyl)-N-alkanoyl tyramines; Cancer Res., 57 702
Properties of DU-14
| Density | 1.089±0.06 g/cm3(Predicted) |
| storage temp. | RT |
| solubility | Soluble in DMSO (up to 25 mg/ml). |
| pka | 8.74±0.70(Predicted) |
| form | solid |
| color | Off-white |
| Stability: | Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months. |
Safety information for DU-14
Computed Descriptors for DU-14
New Products
2-Ethoxyphenol Methyl 2-methoxy-5-sulfamoylbenzoate Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate 3,6-Dichloropyridazine 3,6-Dichloro-4-Isopropylpyridazine 2-[(2-Ethoxyphenoxy)methyl]oxirane m-Tolualdehyde p-Anisaldehyde 2-Bromobenzaldehyde 4-Fluorobenzaldehyde 1-Propyl-4-piperidone 3-Amino-3-(3-fluorophenyl)propanoic acid 6-Methyl-2-pyridinemethanol 2-Pyridinecarboxaldehdye tert-Butyl ((1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate 1-Indanone 2-Chloromethyl-6-methyl-pyridine 4-Morpholinoaniline Abiraterone Ethyl Ether 1-nitro-3,5-dimethyl adamantine (NMEM) Vardenafil Bis-sulphonamide(Dimer) 3-(2-aminoethyl) benzene sulfonamide Nabumetone Impurity 5 2,2-dibromo-1-cyclopropyl-2-(2-fluorophenyl)ethan-1-oneRelated products of tetrahydrofuran
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