DL-ADRENALINE HYDROCHLORIDE

Chemical properties

solid

The Uses of DL-ADRENALINE HYDROCHLORIDE

bronchodilatator,

The Uses of DL-ADRENALINE HYDROCHLORIDE

An adrenergic receptor agonist.

The Uses of DL-ADRENALINE HYDROCHLORIDE

(±)-Epinephrine hydrochloride has been used:

• in the induction of renalase expression in Human renal proximal tubular epithelial cells
• in the infusion studies to test its effect on heart rate and eye temperature measurements in bull
• as a medium supplement for the stimulation of endothelial progenitor cells

What are the applications of Application

(±)-Epinephrine hydrochloride is an adrenergic receptor agonist

General Description

Epinephrine (adrenalin) is synthesized from norepinephrine (noradrenalin) by the action of the enzyme phenylethanolamine N-methyltransferase. Epinephrine comprises 5%-10% of the total catecholamines in the central nervous system. It is a mixed α/β-adrenergic receptor agonist and stimulates these receptors. Their site of synthesis is adrenal medulla and it travels through the vascular systems. Its breakdown occurs in the central nervous system (CNS), liver and kidney.

Biochem/physiol Actions

Epinephrine improves systemic pressure during cardiopulmonary resuscitation and is used post cardiac arrest. The levels of epinephrine increases during trauma, sepsis and hypoglycemia resulting in increased cardiac rate and contractility. It is used in the treatment of acute anaphylaxis. Use of epinephrine hydrochloride enables dilation of pupil during intraocular lens (IOL) implantation surgery.