DIETHYL TRIMETHYLSILYL PHOSPHITE
Synonym(s):Phosphorous acid diethyl trimethylsilylester
- CAS NO.:13716-45-5
- Empirical Formula: C7H19O3PSi
- Molecular Weight: 210.28
- MDL number: MFCD00464673
- EINECS: 237-268-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:18:02
What is DIETHYL TRIMETHYLSILYL PHOSPHITE?
The Uses of DIETHYL TRIMETHYLSILYL PHOSPHITE
Diethyl Trimethylsilyl Phosphite acts as a reagent in the synthesis of substituted N-formylaminomethylenediphosphonates and derivatives. It also functions as a reagent in the synthesis of phosphonic analog of glutamic acid.
The Uses of DIETHYL TRIMETHYLSILYL PHOSPHITE
Diethyl trimethylsilyl phosphite was used in preparation of:
- diethyl 1-aryl-1-cyanomethanephosphonates
- unsymmetrical ketones
- ketones from aldehydes via α-trimethylsiloxy-phosphonates
- phosphonates
What are the applications of Application
Diethyl trimethylsilyl phosphite is a useful ketone synthesis reagent
Purification Methods
Fractionate it under reduced pressure and has 3 1PMR: P -128ppm relative to H3PO4. [Sekine et al. J Org Chem 46 2097 1981, Chernyshev et al. J Gen Chem USSR (Engl Transl) 45 231 1975.]
Properties of DIETHYL TRIMETHYLSILYL PHOSPHITE
| Boiling point: | 58-59 °C10 mm Hg(lit.) |
| Density | 0.921 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | 33 °C |
Safety information for DIETHYL TRIMETHYLSILYL PHOSPHITE
| Signal word | Warning |
| Pictogram(s) |
![]() Flame Flammables GHS02 |
| GHS Hazard Statements |
H226:Flammable liquids |
Computed Descriptors for DIETHYL TRIMETHYLSILYL PHOSPHITE
New Products
2-(2-aminoethyl) benzenesulfonamide Gemcitabine 3-benzoate impurity Dihydroxyphenylacetone Ornidazole EP impurity D Acetyl amino diol impurity Valsartan Benzyl Ester Impurity B N,N'-Dicyclohexylcarbodiimide 3-Bromo-2-Methyl-5-Nitropyridine 5-Bromo-3-Methyl-2-Pyridinecarboxylic acid 2-Amino-4-Methylpyridine 4-Aminopyridine 4-dimethylaminopyridineRelated products of tetrahydrofuran


![2-TRIMETHYLSILOXY-[1,3,2]-DIOXAPHOSPHOLANE](https://img.chemicalbook.in/CAS/GIF/58068-62-5.gif)


![4,4,5,5-TETRAMETHYL-2-TRIMETHYLSILOXY-[1,3,2]-DIOXAPHOSPHOLANE](https://img.chemicalbook.in/CAS/GIF/72666-09-2.gif)

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