Diazo Biotin-PEG3-Azide
Synonym(s):Diazo biotin-azide
- CAS NO.：1339202-33-3
- Empirical Formula: C33H45N9O7S
- Molecular Weight: 711.84
- MDL number: MFCD28334530
- Update Date: 2026-04-24 14:59:07
What is Diazo Biotin-PEG3-Azide?
Description
Diazo Biotin-PEG3-azide is useful for introducing a biotin moiety to alkyne-containing biomolecules using Cu(I)-catalyzed Click Chemistry. The hydrophilic spacer arm provides better solubility to the labeled molecules in aqueous media. Diazo allows efficient release of captured biotinylated molecules from streptavidin using sodium dithionite (Na2S2O4).
The Uses of Diazo Biotin-PEG3-Azide
Azo biotin-azide is a linker that contains a biotin moiety connected to an azide group through a spacer arm containing a diazo group that can be cleaved with 50 mM sodium dithionite solution. The biotin can be captured by streptavidin and the azide can react with terminal or strained alkynes.
Properties of Diazo Biotin-PEG3-Azide
| storage temp. | -20°C |
| form | powder or crystals |
Safety information for Diazo Biotin-PEG3-Azide
Computed Descriptors for Diazo Biotin-PEG3-Azide
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