Diazo Biotin-PEG3-Alkyne
- CAS NO.：1884349-58-9
- Empirical Formula: C39H53N7O9S
- Molecular Weight: 795.94
- MDL number: MFCD28505544
- Update Date: 2026-07-18 07:23:31
What is Diazo Biotin-PEG3-Alkyne?
Description
Diazo Biotin-PEG3-alkyne is useful for introducing a biotin moiety to azide-containing biomolecules using Cu(I)-catalyzed Click Chemistry. The hydrophilic spacer arm provides better solubility to the labeled molecules in aqueous media. Diazo allows efficient release of captured biotinylated molecules from streptavidin using sodium dithionite (Na2S2O4).
The Uses of Diazo Biotin-PEG3-Alkyne
Diazo biotin-alkyne is an alkyne-activated, sodium dithionite (Na2S2O4) cleavable biotin probe that allows for efficient release of the captured biomolecules from streptavidin. This reagent contains a biotin moiety linked to an azide group through a spacer arm containing a diazo group that can be cleaved with 50 mM sodium dithionite solution.
Properties of Diazo Biotin-PEG3-Alkyne
| Boiling point: | 1092.2±65.0 °C(Predicted) |
| Density | 1.31±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | Soluble in DMSO |
| pka | 8.48±0.45(Predicted) |
Safety information for Diazo Biotin-PEG3-Alkyne
Computed Descriptors for Diazo Biotin-PEG3-Alkyne
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