Diacetone-D-glucose
Synonym(s):D -Glucose diacetonide;1,2,5,6-diisopropylidene-D -glucose;Diacetone-D -glucose
- CAS NO.：582-52-5
- Empirical Formula: C12H20O6
- Molecular Weight: 260.28
- MDL number: MFCD00005544
- EINECS: 209-486-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:18:53
What is Diacetone-D-glucose?
Chemical properties
white to light yellow crystal powde
The Uses of Diacetone-D-glucose
Diacetone-D-glucose is mainly used in biochemical reaction and used as medicine intermediate. It is used in synthesize for below products: L-gulose;1,2:5,6-Di-O-isopropylidene-a-D-gulofuranose; Alllose; ;1,2:5,6-Double-O-Isopropylidene-3-C-(1-Methoxycarbonyl)Ethide-alfa-D-Furanose) ;1,2:5,6-Di-O-isopropylidene-a-D-ribo-hexofuranose-3-ulose;6-deoxy idose.
The Uses of Diacetone-D-glucose
1,2:5,6-Di-O-isopropylidene-α-D-glucofuranose is a compound useful in organic synthesis.
Purification Methods
Diacetone-D-glucose crystallises from Et2O, (needles), pet ether or *C6H6 and sublimes in vacuo. It is soluble in 7 volumes of H2O and 200 volumes of pet ether at their boiling points. The solubility in H2O at 17.5o is 4.3%. It precipitates from aqueous solutions on basification with NaOH. [Schmid & Karrer Helv Chim Acta 32 1371 1949, Fischer & Rund Chem Ber 49 90, 93 1916, IR: Kuhn Anal Chem 22 276 1950, Beilstein 19/12 V 318.]
Properties of Diacetone-D-glucose
| Melting point: | 110-111 °C(lit.) |
| Boiling point: | 323.54°C (rough estimate) |
| alpha | -11 º (c=5, EtOH) |
| Density | 1.1432 (rough estimate) |
| refractive index | -18.5 ° (C=5, H2O) |
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| solubility | Chloroform (Slightly), Methanol (Slightly), Water (Slightly, Sonicated) |
| form | Powder |
| pka | 13.15±0.60(Predicted) |
| color | White to yellow |
| optical activity | [α]20/D 18°, c = 1% in H2O |
| Water Solubility | slightly soluble |
| Merck | 14,2965 |
| BRN | 84386 |
| EPA Substance Registry System | Diacetone glucose (582-52-5) |
Safety information for Diacetone-D-glucose
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Diacetone-D-glucose
| InChIKey | KEJGAYKWRDILTF-YENDLIOYSA-N |
Diacetone-D-glucose manufacturer
OCIMUM LIFESCIENCES PVT LTD
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product: 582-52-5 Glucose di acetonoide 97%
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Phone:+91-9879767984
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product: 1,2:5,6-Di-O-isopropylidene-a-D- glucof 582-52-5 99%
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