1,2:5,6-Bis-O-(1-methylethylidene)-D-mannitol
Synonym(s):D -Mannitol diacetonide
- CAS NO.：1707-77-3
- Empirical Formula: C12H22O6
- Molecular Weight: 262.3
- MDL number: MFCD00003211
- EINECS: 216-954-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-09-18 19:10:02
What is 1,2:5,6-Bis-O-(1-methylethylidene)-D-mannitol?
Chemical properties
White Solid
The Uses of 1,2:5,6-Bis-O-(1-methylethylidene)-D-mannitol
Nebivolol intermediate.
What are the applications of Application
1,2:5,6-Di-O-isopropylidene-D-mannitol is a nebivolol intermediate and carbohydrate derivative
Purification Methods
Although quite soluble in H2O, it gives a purer product when crystallised from this solvent, forming needles [Baer J Am Chem Soc 67 338 1945, NMR: Curtis et al. J Chem Soc, Perkin Trans 1 1756 1977]. [Beilstein 19/11 V 589.]
Properties of 1,2:5,6-Bis-O-(1-methylethylidene)-D-mannitol
| Melting point: | 120-122 °C(lit.) |
| Boiling point: | 382.0±32.0 °C(Predicted) |
| alpha | 6 º (c=5, Chloroform) |
| Density | 1.175±0.06 g/cm3(Predicted) |
| refractive index | 6.5 ° (C=8, CHCl3) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | methanol: 100 mg/mL, clear, colorless |
| form | Crystalline Powder |
| pka | 12.98±0.20(Predicted) |
| color | White |
| optical activity | [α]/D +6.0±1.0°, c = 5 in chloroform |
| BRN | 83765 |
| CAS DataBase Reference | 1707-77-3(CAS DataBase Reference) |
| NIST Chemistry Reference | D-Mannitol, 1,2:5,6-bis-o-(1-methylethylidene)-(1707-77-3) |
Safety information for 1,2:5,6-Bis-O-(1-methylethylidene)-D-mannitol
Computed Descriptors for 1,2:5,6-Bis-O-(1-methylethylidene)-D-mannitol
| InChIKey | ODYBCPSCYHAGHA-ZYUZMQFOSA-N |
1,2:5,6-Bis-O-(1-methylethylidene)-D-mannitol manufacturer
Siri Organics
Hyderabad
Phone:91-9490021226
Whatsapp: 91-9490021226
product: 1,2-5,6-di-O-isopropylidene-D-mannitol
Siddhi Vinayaka Spechem Private Limited
Karnataka
product: Diacetone-D-Mannitol, CAS NO1707-77-3,SVS206
ASM Organics
Andhra Pradesh
Phone:91-9866122393
Whatsapp: 91-9866122393
product: 1,2-5,6-di-O-isopropylidene-D-mannitol
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