Di-tert-butyl N,N-diisopropylphosphoramidite
- CAS NO.：137348-86-8
- Empirical Formula: C14H32NO2P
- Molecular Weight: 277.38
- MDL number: MFCD00153506
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:17:31
What is Di-tert-butyl N,N-diisopropylphosphoramidite?
Chemical properties
Clear Colourless Liquid
The Uses of Di-tert-butyl N,N-diisopropylphosphoramidite
A phosphinane derivative with immunomodulating activity.
The Uses of Di-tert-butyl N,N-diisopropylphosphoramidite
Di-tert-butyl N,N-diisopropylphosphoramidite is a general reagent to introduce tert-butyl-protected phosphate groups. It is commonly used in phosphorylation of biomolecules. It can also be used in the synthesis of phosphoramidate-linked glycoconjugates.
Properties of Di-tert-butyl N,N-diisopropylphosphoramidite
| Boiling point: | 85-90 °C/0.2 mmHg (lit.) |
| Density | 0.879 g/mL at 25 °C (lit.) |
| refractive index | n |
| Flash point: | >230 °F |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| pka | 4.90±0.70(Predicted) |
| form | Liquid |
| color | Clear colorless |
| BRN | 4858847 |
| Stability: | Moisture Sensitive |
| CAS DataBase Reference | 137348-86-8(CAS DataBase Reference) |
Safety information for Di-tert-butyl N,N-diisopropylphosphoramidite
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Di-tert-butyl N,N-diisopropylphosphoramidite
| InChIKey | YGFLCNPXEPDANQ-UHFFFAOYSA-N |
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