DEPBT
Synonym(s):3-(Diethoxy-phosphoryloxy)-1,2,3-benzo[d]triazin-4(3H)-one,Diethyl-(4-oxo-3H-1,2,3-benzotriazin-3-yl)phosphate;DEPBT
- CAS NO.：165534-43-0
- Empirical Formula: C11H14N3O5P
- Molecular Weight: 299.22
- MDL number: MFCD01236967
- EINECS: 628-030-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:22:30
What is DEPBT?
Chemical properties
White solid
The Uses of DEPBT
DEPBT is a peptide coupling reagent used in peptide synthesis. It shows remarkable resistance to racemization.
General Description
3-(Diethoxyphosphoryloxy)-1,2,3-benzotriazin-4(3H)-one (DEPBT) is a coupling reagent that facilitates amide bond formation and also resists racemization. It has been shown to be more effective than phosphonium and uronium coupling reagents.
Properties of DEPBT
| Melting point: | 75-77°C |
| Boiling point: | 382.1±25.0 °C(Predicted) |
| Density | 1.45±0.1 g/cm3(Predicted) |
| storage temp. | Store at +2°C to +8°C. |
| solubility | almost transparency in Ethylacetate |
| form | Powder |
| color | White |
| CAS DataBase Reference | 165534-43-0(CAS DataBase Reference) |
Safety information for DEPBT
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for DEPBT
| InChIKey | AJDPNPAGZMZOMN-UHFFFAOYSA-N |
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![5-Chloro-1-[bis(dimethylamino)methylene]-1H-benzotriazolium 3-oxide hexafluorophosphate](https://img.chemicalbook.in/CAS/GIF/330645-87-9.gif)
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