TSTU
Synonym(s):O-(N-Succinimidyl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate;N,N,N′,N′-Tetramethyl-O-(N-succinimidyl)uronium tetrafluoroborate;O-[N-Succinimidyl)-1,1,3,3-tetramethyluronium tetrafluoroborate;TSTU
- CAS NO.：105832-38-0
- Empirical Formula: C9H16BF4N3O3
- Molecular Weight: 301.05
- MDL number: MFCD00077875
- EINECS: 629-651-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:22:19
What is TSTU?
Chemical properties
White crystalline
The Uses of TSTU
TSTU is used as a peptide coupling reagent in solvent systems.
The Uses of TSTU
peptide coupling reagent converts carboxylates to N-succinimidyl active esters
The Uses of TSTU
Reagent for the clean in-situ formation of N-succinimidyl active esters
General Description
N,N,N′,N′-Tetramethyl-O-(N-succinimidyl)uronium tetrafluoroborate is commonly used for the conversion of carboxylic acid into the corresponding N-hydroxysuccinimidyl (NHS) ester.
Properties of TSTU
| Melting point: | 198-201 °C(lit.) |
| Density | 1.41 g/cm |
| storage temp. | 2-8°C |
| solubility | acetonitrile: 0.1 g/mL, clear |
| form | Crystalline Powder or Needles |
| color | White to off-white |
| Sensitive | Moisture Sensitive |
| CAS DataBase Reference | 105832-38-0(CAS DataBase Reference) |
Safety information for TSTU
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for TSTU
| InChIKey | BVYYWTQJMFGHLU-UHFFFAOYSA-M |
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