Decylamine

Synonym(s):1-Aminodecane;NDA

CAS NO.：2016-57-1
Empirical Formula: C10H23N
Molecular Weight: 157.3
MDL number: MFCD00008149
EINECS: 217-957-7
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-28 06:22:12

What is Decylamine?

Chemical properties

It is a clear, colorless, flammable, liquid with a ammonia odor. Slightly soluble in water, easily soluble in ethanol, ether, acetone, benzene and chloroform.

The Uses of Decylamine

Decylamine was used in the synthesis of dynole 2-24 series by undergoing reductive amination with 1-(3-(dimethylamino)propyl)-1H-indole-3-carbaldehyde. It was also used as a coordinating solvent to thermolyse the lead piperidine and lead tetrahydroquinoline dithiocarbamate (DTC) complexes.

The Uses of Decylamine

1-Decylamine is a intermediate forming the phosphatidylcholine-decylamine liposomal membranes.

What are the applications of Application

Decylamine has been used as:
Amine in the synthesis of dynole-2-24 by reductive amination with 1-(3-(dimethylamino)propyl)-1H-indole-3-carbaldehyde.
A modifier in the synthesis of nanocomposites based on poly(butylene terephthalate) and C60 nanoparticles.
A template in the synthesis of ordered two and three dimensional mesoporous iron oxide.

Definition

ChEBI: Decylamine is an alkylamine.

Synthesis Reference(s)

The Journal of Organic Chemistry, 43, p. 2259, 1978 DOI: 10.1021/jo00405a036
Synthesis, p. 450, 1989 DOI: 10.1055/s-1989-27284

General Description

Decylamine is a hydrophobic long alkylated cationic ammonium that is used to modify the polarity of reversed phases on octadecylsilyl (ODS) gels.

Safety Profile

Poison by ingestion and skin contact. A skin irritant. Flammable when exposed to heat or flame; can react with oxidizing materials. To fight fue, use alcohol foam, foam, dry chemical. When heated to decomposition it emits toxic fumes of NOx. See AMINES and AMINES, FATTY.

Properties of Decylamine

Melting point:	12-14 °C(lit.)
Boiling point:	216-218 °C(lit.)
Density	0.787 g/mL at 25 °C(lit.)
refractive index	n20/D 1.436(lit.)
Flash point:	186 °F
storage temp.	room temp
solubility	Chloroform, Ethyl Acetate
form	Liquid
pka	10.64(at 25℃)
color	Clear colorless to yellow or brown
BRN	1735220
Stability:	Stable. Incompatible with strong oxidizing agents, acids, acid chlorides, acid anhydrides. Absorbs carbon dioxide from the air.
CAS DataBase Reference	2016-57-1(CAS DataBase Reference)
NIST Chemistry Reference	1-Decanamine(2016-57-1)
EPA Substance Registry System	Decylamine (2016-57-1)

Safety information for Decylamine

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05 Skull and Crossbones Acute Toxicity GHS06 Environment GHS09
GHS Hazard Statements	H314:Skin corrosion/irritation H410:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P270:Do not eat, drink or smoke when using this product. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.